![]() ![]() biomimetic membranes, diagnostics, biochips, supramolecular medicine, nanoglycobiology, and bioprocess technology). This was surely a system that could be moulded into many applications, and under the guidance of Uwe’s deft hands, became a promising nanobiotechnological platform for a wide range of uses (e.g. Uwe was quick to recognize that S-layers provided a natural nano-scale construction of regularly arranged proteins (and holes) that, under the correct conditions,Ĭould be assembled or disassembled. ![]() Linear (p2), tetragonal (p4), and hexagonal (p3 and p6) lattices were discovered, which proved to be built through self-assembly processes. In his hands, S-layers provided breathtaking images since they are composed of regular arrays of rather large MW (glyco)proteins that could be readily viewed by electron microscopy. During this time, he concentrated on the detection and high-resolution structure of their constituent S (surface)-layers using transmission electron microscopy, quickly becoming a highly respected microscopist who excelled in the cryo-technique of freeze-etching. sphaericus, and several thermophilic clostridia. He began his S-layer studies in the mid-1960s, working primarily on Bacillus stearothermophilus (now Geobacillus), B. Throughout his career, Uwe has had one central focus to determine the structure and function of bacterial S-layers. Sleytr of the Center for NanoBiotechnology, BOKU – University of Natural Resources and Applied Life Sciences in Vienna, Austria. Because of the importance of cell walls, many researchers have spent their whole lives attempting to enlighten the scientific community about a single aspect of a bacterial surface. This book provides an up-to-date knowledge of the prokaryotic cell wall, including its structure, composition, synthesis, assembly, and some surface interactions. Since prokaryotes are the most diverse and ubiquitous life forms on Earth, involved in almost all natural cycles, including elemental cycling and many forms of disease, their surfaces are the required primary interface between the cell and its surroundings, often mediating or catalyzing important interactions. There are two fundamental structural varieties of walls, that is, the Gram-positive or Gramnegative formats, and many bacteria also possess associated structural layers on top of the wall, for example, capsules, sheaths, or S-layers. All prokaryotes, whether they are archaea or bacteria, rely on their surfaces for multiple functions, including being a barrier with their external environment most do this via a cell envelope of which the most important structure is the cell wall. Prokaryote cells are uncomplicated cells possessing a simple design. We offer our condolences and retain him in memory. The death of Terry is not only a great loss for his family but also for his colleagues and the microbiological community. Cover design: WMXDesign GmbH, Heidelberg, Germany Printed on acid-free paper Springer is part of Springer Science+Business Media (Terry passed away shortly after writing the foreword. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The use of general descriptive names, registered names, trademarks, etc. Violations are liable to prosecution under the German Copyright Law. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. ![]() All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. ISBN 978-1-9 e-ISBN 978-2-6 DOI 10.1007/978-2-6 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2010922367 # Springer-Verlag Berlin Heidelberg 2010 This work is subject to copyright. Ajit Varma Director General Amity Institute of Microbial Technology Amity University Uttar Pradesh & Vice Chairman Amity Science, Technology & Innovation Foundation Block A, Amity Campus Sector 125 Noida, UP 201303, India Harald Claus Institute of Microbiology and Wine Research Johannes Gutenberg-University Becherweg 15 55099 Mainz, Germany hc Helmut Ko¨nig Institute of Microbiology and Wine Research Johannes Gutenberg-University Becherweg 15 55099 Mainz, Germany ĭr. Prokaryotic Cell Wall Compounds Structure and BiochemistryĮditors Prof. ![]()
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